AirHint found the following cheapest return flights from Medellin (EOH) to Madrid (MAD) in October 2025 (see full year).

Return flights

25 Oct - 15 Nov	Clic Air
28 Oct - 11 Nov	Satena
24 Oct - 14 Nov	Clic Air
30 Oct - 14 Nov	Satena
25 Oct - 14 Nov	Clic Air
29 Oct - 13 Nov	Satena
29 Oct - 04 Nov	Clic Air
18 Oct - 08 Nov	Clic Air
24 Oct - 15 Nov	Clic Air
21 Oct - 07 Nov	Satena
07 Oct - 14 Oct	Clic Air
09 Oct - 14 Oct	Clic Air

Also check the deals for one-way flights from Medellin to Madrid in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Medellin to Madrid in October from 716€

Return flights