AirHint found the following cheapest return flights from Duesseldorf (DUS) to Prague (PRG) in September 2025 (see full year).

Return flights

19 Sep - 24 Sep	Eurowings	direct
06 Sep - 11 Sep	Eurowings	direct
26 Sep - 30 Sep	Eurowings	direct
12 Sep - 17 Sep	Eurowings	direct
12 Sep - 16 Sep	Eurowings
17 Sep - 19 Sep	Ryanair
29 Sep - 01 Oct	easyJet
21 Sep - 23 Sep	Eurowings	direct
14 Sep - 17 Sep	Eurowings	direct
07 Sep - 11 Sep	Eurowings	direct
22 Sep - 24 Sep	Eurowings	direct
29 Sep - 01 Oct	Eurowings	direct
30 Sep - 07 Oct	Eurowings	direct
27 Sep - 02 Oct	easyJet
29 Sep - 06 Oct	Eurowings	direct
30 Sep - 04 Oct	Eurowings	direct
28 Sep - 05 Oct	Eurowings	direct

Also check the deals for one-way flights from Duesseldorf to Prague in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Prague

Cheap car rent in Prague

Cheapest return flights from Duesseldorf to Prague in September from 100€

Return flights