AirHint found the following cheapest return flights from Duesseldorf (DUS) to Prague (PRG) in December 2025 (see full year).

Return flights

12 Dec - 19 Dec	Eurowings	direct
17 Dec - 20 Dec	easyJet
16 Dec - 20 Dec	easyJet
10 Dec - 13 Dec	Eurowings	direct
16 Dec - 18 Dec	easyJet
15 Dec - 19 Dec	Ryanair
17 Dec - 18 Dec	easyJet
10 Dec - 16 Dec	easyJet
23 Dec - 27 Dec	Eurowings	direct
11 Dec - 13 Dec	Eurowings	direct
23 Dec - 11 Jan	Eurowings
23 Dec - 11 Jan	Eurowings	direct
31 Dec - 05 Jan	Eurowings	direct
29 Dec - 02 Jan	Lufthansa
27 Dec - 01 Jan	LOT
30 Dec - 01 Jan	LOT
30 Dec - 04 Jan	LOT
29 Dec - 03 Jan	LOT
28 Dec - 04 Jan	LOT
31 Dec - 04 Jan	LOT

Also check the deals for one-way flights from Duesseldorf to Prague in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Duesseldorf to Prague in December from 146€

Return flights