AirHint found the following cheapest return flights from Duesseldorf (DUS) to Prague (PRG) in October 2025 (see full year).

Return flights

24 Oct - 31 Oct	Eurowings	direct
23 Oct - 30 Oct	Eurowings	direct
27 Oct - 31 Oct	Eurowings	direct
30 Oct - 31 Oct	Eurowings	direct
27 Oct - 30 Oct	Eurowings	direct
28 Oct - 31 Oct	Eurowings	direct
24 Oct - 29 Oct	Eurowings
23 Oct - 28 Oct	Eurowings	direct
24 Oct - 29 Oct	Eurowings	direct
29 Oct - 31 Oct	Eurowings	direct
30 Oct - 03 Nov	Eurowings
29 Oct - 05 Nov	Eurowings
31 Oct - 03 Nov	Eurowings
31 Oct - 04 Nov	Eurowings
30 Oct - 01 Nov	Eurowings
26 Oct - 01 Nov	easyJet
31 Oct - 01 Nov	Eurowings
27 Oct - 02 Nov	Eurowings
31 Oct - 04 Nov	Eurowings	direct
30 Oct - 02 Nov	Eurowings

Also check the deals for one-way flights from Duesseldorf to Prague in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Prague

Cheap car rent in Prague

Cheapest return flights from Duesseldorf to Prague in October from 137€

Return flights