AirHint found the following cheapest return flights from Detroit (DTW) to Lisbon (LIS) in October 2025 (see full year).

Return flights

07 Oct - 14 Oct	Spirit Airlines
08 Oct - 15 Oct	Spirit Airlines
22 Oct - 29 Oct	Spirit Airlines
15 Oct - 22 Oct	Spirit Airlines
23 Oct - 30 Oct	Spirit Airlines
28 Oct - 04 Nov	Spirit Airlines
14 Oct - 21 Oct	Spirit Airlines
29 Oct - 05 Nov	Spirit Airlines
11 Oct - 18 Oct	Icelandair
20 Oct - 27 Oct	Spirit Airlines
21 Oct - 28 Oct	Spirit Airlines
24 Oct - 31 Oct	Spirit Airlines
27 Oct - 03 Nov	Air Canada
30 Oct - 06 Nov	Air Canada
31 Oct - 07 Nov	jetBlue
25 Oct - 01 Nov	Spirit Airlines
26 Oct - 02 Nov	Virgin Atlantic

Also check the deals for one-way flights from Detroit to Lisbon in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Detroit to Lisbon in October from 441€

Return flights