AirHint found the following cheapest return flights from Detroit (DTW) to Istanbul (IST) in May 2026 (see full year).
Return flights
| 10 May - 28 May | Air France | ||
| 20 May - 13 Jun | Air France | ||
| 13 May - 24 May | Lufthansa | ||
| 10 May - 28 May | Turkish Airlines | direct | |
| 13 May - 24 May | Turkish Airlines | direct |
Also check the deals for one-way flights from Detroit to Istanbul in May.
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