AirHint found the following cheapest return flights from Detroit (DTW) to Istanbul (IST) in April 2026 (see full year).

Return flights

12 Apr - 23 Apr	Delta
15 Apr - 30 Apr	Delta
13 Apr - 20 Apr	Delta
22 Apr - 29 Apr	Delta
20 Apr - 12 May	Delta
14 Apr - 23 Apr	Delta
14 Apr - 29 Apr	Delta
13 Apr - 25 Apr	Delta
16 Apr - 23 Apr	Delta
14 Apr - 27 Apr	Delta
11 Apr - 25 Apr	Delta
20 Apr - 12 May	Turkish Airlines	direct

Also check the deals for one-way flights from Detroit to Istanbul in April.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Detroit to Istanbul in April from 486€

Return flights