AirHint found the following cheapest return flights from Detroit (DTW) to Istanbul (IST) in November 2025 (see full year).

Return flights

15 Nov - 24 Nov	Icelandair
17 Nov - 13 Dec	Spirit Airlines
28 Nov - 11 Dec	Spirit Airlines
27 Nov - 10 Dec	Spirit Airlines
24 Nov - 08 Dec	Spirit Airlines
08 Nov - 17 Nov	Icelandair
28 Nov - 07 Dec	Spirit Airlines
20 Nov - 27 Nov	Icelandair
15 Nov - 06 Dec	Icelandair
15 Nov - 22 Nov	Icelandair
22 Nov - 13 Dec	Spirit Airlines
16 Nov - 01 Dec	Spirit Airlines
28 Nov - 09 Dec	KLM
23 Nov - 13 Dec	KLM
06 Nov - 20 Nov	Spirit Airlines
17 Nov - 19 Nov	Spirit Airlines
13 Nov - 22 Nov	Spirit Airlines
14 Nov - 22 Nov	Spirit Airlines
10 Nov - 17 Nov	Spirit Airlines
15 Nov - 19 Nov	Icelandair

Also check the deals for one-way flights from Detroit to Istanbul in November.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Detroit to Istanbul in November from 394€

Return flights