AirHint found the following cheapest return flights from Detroit (DTW) to Rome (FCO) in November 2025 (see full year).

Return flights

07 Nov - 18 Nov	Spirit Airlines
03 Nov - 07 Nov	Spirit Airlines
10 Nov - 06 Dec	Spirit Airlines
16 Nov - 22 Nov	Spirit Airlines
13 Nov - 06 Dec	Spirit Airlines
27 Nov - 04 Dec	Spirit Airlines
12 Nov - 06 Dec	Spirit Airlines
19 Nov - 25 Nov	Spirit Airlines
22 Nov - 01 Dec	Spirit Airlines
27 Nov - 04 Dec	KLM	direct
20 Nov - 22 Nov	Spirit Airlines
13 Nov - 06 Dec	KLM	direct
10 Nov - 17 Nov	Icelandair
06 Nov - 13 Nov	Icelandair
20 Nov - 27 Nov	Icelandair
20 Nov - 22 Nov	KLM	direct

Also check the deals for one-way flights from Detroit to Rome in November.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Detroit to Rome in November from 417€

Return flights