AirHint found the following cheapest return flights from Detroit (DTW) to Brussels (BRU) in October 2025 (see full year).

Return flights

20 Oct - 27 Oct	Spirit Airlines
21 Oct - 04 Nov	Spirit Airlines
29 Oct - 12 Nov	Spirit Airlines
21 Oct - 28 Oct	Spirit Airlines
26 Oct - 02 Nov	Spirit Airlines
26 Oct - 03 Nov	Spirit Airlines
22 Oct - 29 Oct	Spirit Airlines
14 Oct - 21 Oct	Spirit Airlines
20 Oct - 04 Nov	Spirit Airlines
21 Oct - 15 Nov	Icelandair
22 Oct - 15 Nov	Spirit Airlines
20 Oct - 15 Nov	Spirit Airlines
14 Oct - 02 Nov	Icelandair
21 Oct - 12 Nov	Icelandair
14 Oct - 20 Oct	United
22 Oct - 28 Oct	United
14 Oct - 28 Oct	United
14 Oct - 26 Oct	United
14 Oct - 29 Oct	United
20 Oct - 29 Oct	United

Also check the deals for one-way flights from Detroit to Brussels in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Detroit to Brussels in October from 388€

Return flights