AirHint found the following cheapest return flights from Des Moines (DSM) to Cancun (CUN) in December 2025 (see full year).

Return flights

22 Dec - 29 Dec	Frontier Airlines
08 Dec - 12 Dec	Delta
20 Dec - 26 Dec	Allegiant Air
22 Dec - 27 Dec	Frontier Airlines
24 Dec - 03 Jan	Allegiant Air
28 Dec - 04 Jan	Allegiant Air
26 Dec - 02 Jan	Frontier Airlines

Also check the deals for one-way flights from Des Moines to Cancun in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Des Moines to Cancun in December from 365€

Return flights