AirHint found the following cheapest return flights from Cuzco (CUZ) to Santiago (SCL) in December 2025 (see full year).

Return flights

02 Dec - 09 Dec	JetSmart
02 Dec - 08 Dec	JetSmart
03 Dec - 09 Dec	JetSmart
03 Dec - 08 Dec	JetSmart
06 Dec - 09 Dec	JetSmart
05 Dec - 09 Dec	JetSmart
06 Dec - 08 Dec	JetSmart
05 Dec - 08 Dec	JetSmart
02 Dec - 10 Dec	JetSmart
30 Dec - 17 Jan	JetSmart
30 Dec - 12 Jan	JetSmart
30 Dec - 13 Jan	JetSmart
02 Dec - 04 Dec	JetSmart
30 Dec - 14 Jan	JetSmart
30 Dec - 05 Jan	JetSmart
30 Dec - 07 Jan	JetSmart
16 Dec - 05 Jan	JetSmart
31 Dec - 20 Jan	JetSmart
31 Dec - 13 Jan	JetSmart
15 Dec - 05 Jan	JetSmart

Also check the deals for one-way flights from Cuzco to Santiago in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Cuzco to Santiago in December from 177€

Return flights