AirHint found the following cheapest return flights from Cuzco (CUZ) to Santiago (SCL) in December 2025 (see full year).

Return flights

31 Dec - 20 Jan	JetSmart
31 Dec - 21 Jan	JetSmart
30 Dec - 20 Jan	JetSmart
29 Dec - 18 Jan	JetSmart
31 Dec - 18 Jan	JetSmart
29 Dec - 19 Jan	JetSmart
31 Dec - 19 Jan	JetSmart
28 Dec - 14 Jan	JetSmart
29 Dec - 14 Jan	JetSmart
31 Dec - 14 Jan	JetSmart
28 Dec - 31 Dec	JetSmart
29 Dec - 31 Dec	JetSmart
30 Dec - 31 Dec	JetSmart
27 Dec - 31 Dec	JetSmart
28 Dec - 30 Dec	JetSmart
27 Dec - 30 Dec	JetSmart
28 Dec - 29 Dec	JetSmart
27 Dec - 29 Dec	JetSmart
29 Dec - 30 Dec	JetSmart

Also check the deals for one-way flights from Cuzco to Santiago in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Cuzco to Santiago in December from 329€

Return flights