AirHint found the following cheapest return flights from Cancun (CUN) to Panama City (PTY) in December 2025 (see full year).
Return flights
| 06 Dec - 10 Dec | Aeromexico | ||
| 06 Dec - 10 Dec | Copa | direct | |
| 29 Dec - 24 Jan | Copa | direct | |
| 27 Dec - 17 Jan | Copa | direct | |
| 16 Dec - 08 Jan | Copa | direct | |
| 29 Dec - 05 Jan | Copa | direct | |
| 20 Dec - 05 Jan | Copa | direct |
Also check the deals for one-way flights from Cancun to Panama City in December.
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