AirHint found the following cheapest return flights from Cancun (CUN) to Panama City (PTY) in December 2025 (see full year).

Return flights

27 Dec - 17 Jan	Copa	direct
28 Dec - 04 Jan	Copa	direct
30 Dec - 04 Jan	Copa	direct
29 Dec - 05 Jan	Copa	direct
29 Dec - 19 Jan	Viva
29 Dec - 12 Jan	Viva
25 Dec - 02 Jan	Copa	direct
29 Dec - 16 Jan	Viva
29 Dec - 14 Jan	Viva
26 Dec - 12 Jan	Viva
25 Dec - 26 Dec	Viva
26 Dec - 27 Dec	Viva
25 Dec - 27 Dec	Viva

Also check the deals for one-way flights from Cancun to Panama City in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Cancun to Panama City in December from 266€

Return flights