AirHint found the following cheapest return flights from Cancun (CUN) to Panama City (PTY) in December 2025 (see full year).

Return flights

09 Dec - 10 Dec	Aeromexico
11 Dec - 13 Dec	Aeromexico
06 Dec - 11 Dec	Avianca
30 Dec - 08 Jan	Copa	direct
28 Dec - 07 Jan	Copa	direct
16 Dec - 08 Jan	Copa	direct
11 Dec - 14 Dec	Avianca
13 Dec - 14 Dec	Aeromexico
21 Dec - 04 Jan	Copa	direct
11 Dec - 13 Dec	Copa	direct
13 Dec - 14 Dec	Copa	direct
11 Dec - 14 Dec	Copa	direct
12 Dec - 14 Dec	Copa	direct
22 Dec - 26 Dec	Copa	direct
26 Dec - 02 Jan	Copa	direct
06 Dec - 10 Jan	Copa	direct
28 Dec - 18 Jan	Viva
29 Dec - 18 Jan	Viva
29 Dec - 07 Jan	Viva
23 Dec - 07 Jan	Viva

Also check the deals for one-way flights from Cancun to Panama City in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Cancun to Panama City in December from 228€

Return flights