AirHint found the following cheapest return flights from Cancun (CUN) to Rio Negro (MDE) in September 2025 (see full year).

Return flights

23 Sep - 27 Sep	Avianca	direct
26 Sep - 29 Sep	Avianca	direct
02 Sep - 09 Sep	Avianca	direct
08 Sep - 15 Sep	Avianca	direct
22 Sep - 29 Sep	Avianca	direct
17 Sep - 23 Sep	Avianca	direct
20 Sep - 26 Sep	Avianca	direct
10 Sep - 15 Sep	Avianca	direct
10 Sep - 14 Sep	Avianca	direct
08 Sep - 14 Sep	Avianca	direct
26 Sep - 02 Oct	Avianca	direct
24 Sep - 01 Oct	Avianca	direct
25 Sep - 02 Oct	Copa
25 Sep - 03 Oct	Copa
25 Sep - 02 Oct	Avianca	direct
26 Sep - 04 Oct	Avianca	direct
25 Sep - 03 Oct	Avianca	direct

Also check the deals for one-way flights from Cancun to Rio Negro in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Rio Negro

Cheap car rent in Rio Negro

Cheapest return flights from Cancun to Rio Negro in September from 229€

Return flights