AirHint found the following cheapest return flights from Cancun (CUN) to Rio Negro (MDE) in October 2025 (see full year).

Return flights

16 Oct - 19 Oct	Avianca
24 Oct - 07 Nov	Avianca
17 Oct - 21 Oct	Avianca	direct
16 Oct - 21 Oct	Avianca	direct
22 Oct - 28 Oct	Avianca	direct
10 Oct - 17 Oct	Copa
15 Oct - 20 Oct	Copa
10 Oct - 19 Oct	Copa
02 Oct - 06 Oct	Copa
10 Oct - 20 Oct	Copa
02 Oct - 06 Oct	Avianca	direct

Also check the deals for one-way flights from Cancun to Rio Negro in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Rio Negro

Cheap car rent in Rio Negro

Cheapest return flights from Cancun to Rio Negro in October from 225€

Return flights