AirHint found the following cheapest return flights from Cartagena (CTG) to Santiago (SCL) in December 2025 (see full year).

Return flights

27 Dec - 22 Jan	Avianca
30 Dec - 20 Jan	JetSmart
30 Dec - 19 Jan	JetSmart
24 Dec - 31 Dec	Copa
30 Dec - 18 Jan	JetSmart
29 Dec - 19 Jan	JetSmart
29 Dec - 18 Jan	JetSmart
31 Dec - 20 Jan	JetSmart
30 Dec - 08 Jan	JetSmart
30 Dec - 07 Jan	JetSmart
29 Dec - 08 Jan	JetSmart
30 Dec - 31 Dec	JetSmart
29 Dec - 31 Dec	JetSmart
28 Dec - 31 Dec	JetSmart
25 Dec - 31 Dec	JetSmart
25 Dec - 29 Dec	Avianca
26 Dec - 31 Dec	JetSmart
27 Dec - 31 Dec	JetSmart
22 Dec - 31 Dec	JetSmart
21 Dec - 31 Dec	JetSmart

Also check the deals for one-way flights from Cartagena to Santiago in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Cartagena to Santiago in December from 414€

Return flights