AirHint found the following cheapest return flights from Cartagena (CTG) to Santiago (SCL) in December 2025 (see full year).

Return flights

18 Dec - 01 Jan	JetSmart
18 Dec - 08 Jan	JetSmart
31 Dec - 17 Jan	JetSmart
18 Dec - 22 Dec	JetSmart
19 Dec - 01 Jan	JetSmart
26 Dec - 01 Jan	JetSmart
19 Dec - 08 Jan	JetSmart
26 Dec - 08 Jan	JetSmart
26 Dec - 13 Jan	JetSmart
15 Dec - 01 Jan	JetSmart
16 Dec - 01 Jan	JetSmart
03 Dec - 07 Dec	JetSmart
04 Dec - 07 Dec	JetSmart
19 Dec - 22 Dec	JetSmart
15 Dec - 22 Dec	JetSmart
16 Dec - 22 Dec	JetSmart
01 Dec - 07 Dec	JetSmart
09 Dec - 22 Dec	JetSmart
08 Dec - 22 Dec	JetSmart
03 Dec - 09 Dec	JetSmart

Also check the deals for one-way flights from Cartagena to Santiago in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Cartagena to Santiago in December from 332€

Return flights