AirHint found the following cheapest return flights from Cartagena (CTG) to Santiago (SCL) in December 2025 (see full year).

Return flights

04 Dec - 11 Dec	JetSmart
04 Dec - 12 Dec	JetSmart
18 Dec - 04 Jan	JetSmart
15 Dec - 04 Jan	JetSmart
04 Dec - 07 Dec	JetSmart
24 Dec - 11 Jan	JetSmart
22 Dec - 11 Jan	JetSmart
10 Dec - 12 Dec	JetSmart
24 Dec - 04 Jan	JetSmart
04 Dec - 08 Dec	JetSmart
23 Dec - 11 Jan	JetSmart
22 Dec - 04 Jan	JetSmart
04 Dec - 06 Dec	JetSmart
23 Dec - 04 Jan	JetSmart
17 Dec - 04 Jan	JetSmart
04 Dec - 15 Dec	JetSmart
28 Dec - 25 Jan	JetSmart
04 Dec - 09 Dec	JetSmart
10 Dec - 11 Dec	JetSmart
04 Dec - 13 Dec	JetSmart

Also check the deals for one-way flights from Cartagena to Santiago in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Cartagena to Santiago in December from 341€

Return flights