AirHint found the following cheapest return flights from Cartagena (CTG) to Santiago (SCL) in October 2025 (see full year).

Return flights

06 Oct - 26 Oct	JetSmart
19 Oct - 26 Oct	JetSmart
24 Oct - 10 Nov	JetSmart
22 Oct - 10 Nov	JetSmart
19 Oct - 02 Nov	JetSmart
26 Oct - 03 Nov	JetSmart
24 Oct - 26 Oct	JetSmart
22 Oct - 26 Oct	JetSmart
26 Oct - 10 Nov	JetSmart
24 Oct - 02 Nov	JetSmart
22 Oct - 02 Nov	JetSmart
06 Oct - 19 Oct	JetSmart
19 Oct - 03 Nov	JetSmart
26 Oct - 02 Nov	JetSmart
24 Oct - 13 Nov	JetSmart
03 Oct - 12 Oct	Avianca
10 Oct - 17 Oct	Avianca
05 Oct - 26 Oct	JetSmart
06 Oct - 16 Oct	JetSmart
06 Oct - 17 Oct	JetSmart

Also check the deals for one-way flights from Cartagena to Santiago in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Cartagena to Santiago in October from 293€

Return flights