AirHint found the following cheapest return flights from Cartagena (CTG) to Madrid (MAD) in September 2025 (see full year).

Return flights

30 Sep - 08 Oct	Avianca
30 Sep - 07 Oct	Avianca
30 Sep - 21 Oct	Avianca
30 Sep - 20 Oct	Avianca
29 Sep - 09 Oct	Copa
30 Sep - 18 Oct	Avianca
23 Sep - 30 Sep	Avianca
25 Sep - 01 Oct	Spirit Airlines
28 Sep - 25 Oct	Arajet
26 Sep - 16 Oct	Spirit Airlines
27 Sep - 15 Oct	JetSmart
24 Sep - 29 Sep	Spirit Airlines
20 Sep - 27 Sep	JetSmart
19 Sep - 26 Sep	Avianca
22 Sep - 28 Sep	Avianca
20 Sep - 29 Sep	LATAM Airlines Group
20 Sep - 30 Sep	JetSmart
21 Sep - 30 Sep	Avianca
20 Sep - 28 Sep	KLM
18 Sep - 29 Sep	Wingo

Also check the deals for one-way flights from Cartagena to Madrid in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Cartagena to Madrid in September from 761€

Return flights