AirHint found the following cheapest return flights from Cartagena (CTG) to Madrid (MAD) in December 2025 (see full year).

Return flights

10 Dec - 23 Dec	SWISS
25 Dec - 28 Jan	KLM
27 Dec - 23 Jan	KLM
10 Dec - 01 Jan	Avianca
24 Dec - 18 Jan	KLM
22 Dec - 27 Dec	Plus Ultra Lineas Aereas
29 Dec - 05 Jan	KLM
29 Dec - 14 Jan	Plus Ultra Lineas Aereas
22 Dec - 21 Jan	Avianca
10 Dec - 20 Dec	SWISS
26 Dec - 02 Jan	KLM
10 Dec - 22 Dec	Plus Ultra Lineas Aereas
21 Dec - 22 Jan	KLM
16 Dec - 06 Jan	Avianca
08 Dec - 22 Dec	Plus Ultra Lineas Aereas
15 Dec - 22 Dec	Plus Ultra Lineas Aereas
13 Dec - 22 Dec	Plus Ultra Lineas Aereas
13 Dec - 29 Dec	Plus Ultra Lineas Aereas
17 Dec - 28 Dec	KLM
13 Dec - 27 Dec	KLM

Also check the deals for one-way flights from Cartagena to Madrid in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Cartagena to Madrid in December from 701€

Return flights