AirHint found the following cheapest return flights from Cartagena (CTG) to Madrid (MAD) in October 2025 (see full year).

Return flights

29 Oct - 08 Nov	SWISS
17 Oct - 26 Nov	KLM
16 Oct - 19 Nov	KLM
22 Oct - 05 Nov	KLM
27 Oct - 05 Nov	KLM
08 Oct - 23 Oct	Plus Ultra Lineas Aereas
28 Oct - 12 Nov	KLM
26 Oct - 27 Nov	KLM
27 Oct - 27 Nov	KLM
28 Oct - 19 Nov	KLM
09 Oct - 25 Oct	Plus Ultra Lineas Aereas
28 Oct - 07 Nov	Avianca
13 Oct - 29 Oct	KLM
03 Oct - 30 Oct	Spirit Airlines
15 Oct - 23 Oct	KLM
12 Oct - 26 Oct	Arajet
24 Oct - 27 Oct	Avianca
08 Oct - 22 Oct	KLM
15 Oct - 22 Oct	KLM
15 Oct - 31 Oct	KLM

Also check the deals for one-way flights from Cartagena to Madrid in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Cartagena to Madrid in October from 579€

Return flights