AirHint found the following cheapest return flights from Cartagena (CTG) to Madrid (MAD) in October 2025 (see full year).

Return flights

29 Oct - 18 Nov	SWISS
29 Oct - 12 Nov	SWISS
25 Oct - 09 Nov	KLM
23 Oct - 04 Nov	KLM
08 Oct - 04 Nov	KLM
19 Oct - 04 Nov	KLM
19 Oct - 23 Nov	KLM
15 Oct - 15 Nov	KLM
28 Oct - 19 Nov	KLM
13 Oct - 10 Nov	KLM
10 Oct - 31 Oct	Spirit Airlines
09 Oct - 16 Oct	Spirit Airlines
02 Oct - 16 Oct	Spirit Airlines
04 Oct - 24 Oct	KLM
14 Oct - 21 Oct	KLM
01 Oct - 16 Oct	Spirit Airlines
03 Oct - 16 Oct	Spirit Airlines
11 Oct - 23 Oct	Spirit Airlines
08 Oct - 28 Oct	KLM
09 Oct - 23 Oct	Avianca

Also check the deals for one-way flights from Cartagena to Madrid in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Cartagena to Madrid in October from 579€

Return flights