AirHint found the following cheapest return flights from Charlotte (CLT) to Rio Negro (MDE) in December 2025 (see full year).

Return flights

03 Dec - 09 Dec	Spirit Airlines
02 Dec - 09 Dec	Spirit Airlines
03 Dec - 05 Dec	Spirit Airlines
02 Dec - 05 Dec	Spirit Airlines
03 Dec - 04 Dec	Spirit Airlines
02 Dec - 04 Dec	Spirit Airlines
03 Dec - 15 Dec	Spirit Airlines
02 Dec - 15 Dec	Spirit Airlines
03 Dec - 21 Dec	Spirit Airlines
02 Dec - 21 Dec	Spirit Airlines
27 Dec - 07 Jan	Spirit Airlines
20 Dec - 01 Jan	Spirit Airlines
18 Dec - 03 Jan	Copa
14 Dec - 03 Jan	Spirit Airlines
28 Dec - 03 Jan	Spirit Airlines
24 Dec - 03 Jan	Spirit Airlines
26 Dec - 03 Jan	Spirit Airlines

Also check the deals for one-way flights from Charlotte to Rio Negro in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Rio Negro

Cheap car rent in Rio Negro

Cheapest return flights from Charlotte to Rio Negro in December from 243€

Return flights