AirHint found the following cheapest return flights from Charlotte (CLT) to Rome (FCO) in April 2026 (see full year).

Return flights

15 Apr - 22 Apr	Spirit Airlines
14 Apr - 29 Apr	Spirit Airlines
28 Apr - 05 May	Spirit Airlines
13 Apr - 20 Apr	Frontier Airlines
22 Apr - 28 Apr	Spirit Airlines
30 Apr - 08 May	Spirit Airlines
10 Apr - 17 Apr	Air Canada
28 Apr - 28 May	Spirit Airlines
16 Apr - 22 Apr	Finnair	direct
10 Apr - 20 Apr	Spirit Airlines
13 Apr - 24 Apr	Frontier Airlines
12 Apr - 19 Apr	Lufthansa
01 Apr - 08 Apr	Spirit Airlines
27 Apr - 09 May	Lufthansa
28 Apr - 05 May	British Airways	direct

Also check the deals for one-way flights from Charlotte to Rome in April.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Charlotte to Rome in April from 409€

Return flights