AirHint found the following cheapest return flights from Rome (CIA) to Prague (PRG) in May 2026 (see full year).

Return flights

30 May - 03 Jun	Ryanair	direct
30 May - 04 Jun	Ryanair	direct
07 May - 11 May	Ryanair	direct
08 May - 11 May	Ryanair	direct
30 May - 12 Jun	Ryanair	direct
07 May - 10 May	Ryanair	direct
30 May - 01 Jun	Ryanair	direct
30 May - 08 Jun	Ryanair	direct
30 May - 30 May	Ryanair	direct
08 May - 10 May	Ryanair	direct

Also check the deals for one-way flights from Rome to Prague in May.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Rome to Prague in May from 131€

Return flights