AirHint found the following cheapest return flights from Rome (CIA) to Prague (PRG) in April 2026 (see full year).

Return flights

13 Apr - 19 Apr	Ryanair	direct
17 Apr - 19 Apr	Ryanair	direct
10 Apr - 19 Apr	Ryanair	direct
12 Apr - 19 Apr	Ryanair	direct
13 Apr - 01 May	Ryanair	direct
17 Apr - 01 May	Ryanair	direct
10 Apr - 01 May	Ryanair	direct
12 Apr - 01 May	Ryanair	direct

Also check the deals for one-way flights from Rome to Prague in April.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Rome to Prague in April from 150€

Return flights