AirHint found the following cheapest return flights from Rome (CIA) to Osaka (KIX) in September 2025 (see full year).

Return flights

21 Sep - 07 Oct	Ryanair
01 Sep - 11 Sep	Ryanair
04 Sep - 14 Sep	Ryanair
28 Sep - 13 Oct	Ryanair
04 Sep - 06 Sep	Ryanair
04 Sep - 13 Sep	Ryanair
04 Sep - 19 Sep	Ryanair
01 Sep - 13 Sep	Ryanair
03 Sep - 10 Sep	Ryanair
03 Sep - 06 Sep	Ryanair
08 Sep - 13 Sep	Ryanair
19 Sep - 24 Sep	Ryanair

Also check the deals for one-way flights from Rome to Osaka in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Rome to Osaka in September from 735€

Return flights