AirHint found the following cheapest return flights from Brussels (BRU) to Santiago (SCL) in December 2025 (see full year).

Return flights

01 Dec - 09 Dec	Lufthansa
04 Dec - 08 Dec	Lufthansa
04 Dec - 07 Dec	Lufthansa
03 Dec - 06 Dec	TAP
10 Dec - 23 Dec	Lufthansa
27 Dec - 18 Jan	Ryanair
27 Dec - 21 Jan	Ryanair
26 Dec - 18 Jan	TAP
23 Dec - 14 Jan	Ryanair
05 Dec - 25 Dec	TAP
30 Dec - 15 Jan	Ryanair
24 Dec - 15 Jan	Ryanair
11 Dec - 16 Jan	Ryanair
14 Dec - 30 Dec	Ryanair
23 Dec - 10 Jan	Ryanair
25 Dec - 17 Jan	TAP
10 Dec - 26 Dec	Ryanair
24 Dec - 14 Jan	Vueling Airlines
12 Dec - 26 Dec	Ryanair
17 Dec - 25 Dec	Ryanair

Also check the deals for one-way flights from Brussels to Santiago in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Brussels to Santiago in December from 732€

Return flights