AirHint found the following cheapest return flights from Brussels (BRU) to Istanbul (IST) in September 2025 (see full year).

Return flights

23 Sep - 26 Sep	Wizz Air
17 Sep - 24 Sep	Wizz Air
22 Sep - 01 Oct	Wizz Air
16 Sep - 23 Sep	Wizz Air
10 Sep - 19 Sep	Wizz Air
17 Sep - 19 Sep	Wizz Air
02 Sep - 11 Sep	Wizz Air
24 Sep - 16 Oct	Wizz Air
01 Sep - 08 Sep	Wizz Air
03 Sep - 10 Sep	Wizz Air
02 Sep - 08 Sep	Wizz Air
18 Sep - 23 Sep	Wizz Air
24 Sep - 16 Oct	Pegasus Airlines	direct
30 Sep - 11 Oct	Wizz Air
30 Sep - 10 Oct	Wizz Air
30 Sep - 22 Oct	Wizz Air
25 Sep - 01 Oct	Wizz Air
30 Sep - 07 Oct	Wizz Air
29 Sep - 04 Oct	Wizz Air
27 Sep - 02 Oct	AJet

Also check the deals for one-way flights from Brussels to Istanbul in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Brussels to Istanbul in September from 127€

Return flights