AirHint found the following cheapest return flights from Brussels (BRU) to Istanbul (IST) in May 2026 (see full year).

Return flights

28 May - 20 Jun	Aegean Airlines
29 May - 05 Jun	Aegean Airlines
22 May - 27 May	Lufthansa
13 May - 17 May	Wizz Air Malta
19 May - 22 May	Wizz Air Malta
20 May - 25 May	Wizz Air Malta
19 May - 23 May	Wizz Air Malta
28 May - 20 Jun	Turkish Airlines	direct
12 May - 16 May	Wizz Air
01 May - 04 May	Aegean Airlines
18 May - 23 May	Aegean Airlines
21 May - 25 May	Aegean Airlines
13 May - 18 May	Lufthansa
29 May - 05 Jun	Turkish Airlines	direct

Also check the deals for one-way flights from Brussels to Istanbul in May.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Brussels to Istanbul in May from 218€

Return flights