AirHint found the following cheapest return flights from Brussels (BRU) to Istanbul (IST) in October 2025 (see full year).

Return flights

09 Oct - 12 Oct	Wizz Air
07 Oct - 12 Oct	Wizz Air Malta
06 Oct - 09 Oct	Wizz Air
07 Oct - 10 Oct	Wizz Air
05 Oct - 08 Oct	Wizz Air
05 Oct - 12 Oct	Wizz Air
08 Oct - 12 Oct	Wizz Air
02 Oct - 11 Oct	Wizz Air
07 Oct - 15 Oct	Wizz Air Malta
06 Oct - 10 Oct	Wizz Air
07 Oct - 25 Nov	Wizz Air Malta
31 Oct - 16 Nov	Pegasus Airlines	direct
07 Oct - 25 Nov	AJet	direct
27 Oct - 03 Nov	Air Serbia
29 Oct - 03 Nov	Air Serbia
31 Oct - 03 Nov	Pegasus Airlines
25 Oct - 02 Nov	Aegean Airlines
16 Oct - 05 Nov	SKY express
27 Oct - 09 Nov	Wizz Air
16 Oct - 02 Nov	SKY express

Also check the deals for one-way flights from Brussels to Istanbul in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Brussels to Istanbul in October from 139€

Return flights