AirHint found the following cheapest return flights from Asuncion (ASU) to Santiago (SCL) in December 2025 (see full year).

Return flights

02 Dec - 19 Dec	JetSmart
25 Dec - 07 Jan	JetSmart
27 Dec - 07 Jan	JetSmart
28 Dec - 07 Jan	JetSmart
26 Dec - 07 Jan	JetSmart
25 Dec - 15 Jan	JetSmart
27 Dec - 15 Jan	JetSmart
28 Dec - 15 Jan	JetSmart
26 Dec - 15 Jan	JetSmart
03 Dec - 10 Dec	LATAM Airlines Group	direct

Also check the deals for one-way flights from Asuncion to Santiago in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Santiago

Cheap car rent in Santiago

Cheapest return flights from Asuncion to Santiago in December from 226€

Return flights