AirHint found the following cheapest return flights from Asuncion (ASU) to Santiago (SCL) in December 2025 (see full year).

Return flights

21 Dec - 04 Jan	JetSmart
21 Dec - 09 Jan	JetSmart
28 Dec - 04 Jan	JetSmart
28 Dec - 09 Jan	JetSmart
21 Dec - 11 Jan	JetSmart
21 Dec - 07 Jan	JetSmart
28 Dec - 11 Jan	JetSmart
28 Dec - 07 Jan	JetSmart
26 Dec - 04 Jan	JetSmart
30 Dec - 04 Jan	JetSmart
17 Dec - 22 Dec	Aerolineas Argentinas
03 Dec - 14 Dec	Copa

Also check the deals for one-way flights from Asuncion to Santiago in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Santiago

Cheap car rent in Santiago

Cheapest return flights from Asuncion to Santiago in December from 238€

Return flights