AirHint found the following cheapest return flights from Asuncion (ASU) to Santiago (SCL) in October 2025 (see full year).

Return flights

11 Oct - 24 Oct	JetSmart
06 Oct - 24 Oct	JetSmart
13 Oct - 24 Oct	JetSmart
06 Oct - 10 Oct	JetSmart
11 Oct - 28 Oct	JetSmart
13 Oct - 28 Oct	JetSmart
11 Oct - 29 Oct	JetSmart
11 Oct - 20 Oct	JetSmart
16 Oct - 24 Oct	JetSmart
06 Oct - 20 Oct	JetSmart

Also check the deals for one-way flights from Asuncion to Santiago in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Asuncion to Santiago in October from 222€

Return flights