AirHint found the following cheapest return flights from Asuncion (ASU) to Madrid (MAD) in September 2025 (see full year).

Return flights

28 Sep - 17 Oct	LATAM Airlines Group
30 Sep - 17 Oct	GOL Linhas Aéreas
17 Sep - 25 Sep	LATAM Airlines Group
17 Sep - 18 Sep	Avianca
20 Sep - 18 Oct	LATAM Airlines Group
12 Sep - 04 Oct	Avianca
04 Sep - 18 Sep	GOL Linhas Aéreas
17 Sep - 08 Oct	LATAM Airlines Group
28 Sep - 17 Oct	Air Europa	direct
30 Sep - 17 Oct	Air Europa	direct
21 Sep - 28 Sep	Avianca
17 Sep - 24 Sep	LATAM Airlines Group
12 Sep - 30 Sep	Avianca
24 Sep - 22 Oct	Air Europa	direct
12 Sep - 27 Sep	Avianca
30 Sep - 12 Oct	Air Europa	direct
12 Sep - 29 Sep	Avianca
25 Sep - 25 Oct	Air Europa	direct
07 Sep - 09 Sep	Avianca
19 Sep - 28 Sep	LATAM Airlines Group

Also check the deals for one-way flights from Asuncion to Madrid in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Asuncion to Madrid in September from 841€

Return flights