AirHint found the following cheapest return flights from Asuncion (ASU) to Madrid (MAD) in September 2025 (see full year).

Return flights

30 Sep - 17 Oct	GOL Linhas Aéreas
30 Sep - 14 Oct	GOL Linhas Aéreas
28 Sep - 06 Oct	LATAM Airlines Group
24 Sep - 15 Oct	Avianca
24 Sep - 02 Oct	Avianca
24 Sep - 09 Oct	Avianca
26 Sep - 14 Oct	Avianca
26 Sep - 15 Oct	Avianca
29 Sep - 06 Oct	LATAM Airlines Group
27 Sep - 06 Oct	LATAM Airlines Group
21 Sep - 28 Sep	Copa
26 Sep - 29 Sep	Avianca
21 Sep - 27 Sep	Copa
25 Sep - 29 Sep	Copa
23 Sep - 29 Sep	Copa
20 Sep - 26 Sep	LATAM Airlines Group
22 Sep - 27 Sep	Copa
21 Sep - 30 Sep	Copa
21 Sep - 22 Sep	LATAM Airlines Group
23 Sep - 30 Sep	Copa

Also check the deals for one-way flights from Asuncion to Madrid in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Asuncion to Madrid in September from 922€

Return flights