AirHint found the following cheapest return flights from Arequipa (AQP) to Madrid (MAD) in December 2025 (see full year).
Return flights
| 05 Dec - 14 Dec | JetSmart | ||
| 28 Dec - 10 Jan | LATAM Airlines Group |
Also check the deals for one-way flights from Arequipa to Madrid in December.
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