AirHint found the following cheapest return flights from Amsterdam (AMS) to Southampton (SOU) in September 2025 (see full year).

Return flights

19 Sep - 29 Sep	easyJet	direct
29 Sep - 06 Oct	easyJet	direct
05 Sep - 08 Sep	easyJet	direct
19 Sep - 22 Sep	easyJet	direct
05 Sep - 07 Sep	easyJet
27 Sep - 29 Sep	Ryanair
26 Sep - 28 Sep	easyJet
27 Sep - 29 Sep	KLM	direct
01 Sep - 03 Sep	easyJet	direct
29 Sep - 05 Oct	easyJet
28 Sep - 15 Oct	KLM	direct
06 Sep - 13 Sep	Ryanair
29 Sep - 05 Oct	KLM	direct

Also check the deals for one-way flights from Amsterdam to Southampton in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Amsterdam to Southampton in September from 86€

Return flights