AirHint found the following cheapest return flights from Amsterdam (AMS) to Santiago (SCL) in September 2025 (see full year).

Return flights

18 Sep - 26 Sep	Delta
16 Sep - 24 Sep	Delta
16 Sep - 26 Sep	Delta
23 Sep - 15 Oct	Delta
24 Sep - 15 Oct	Delta
25 Sep - 05 Oct	Delta
24 Sep - 16 Oct	Delta
25 Sep - 16 Oct	Delta
23 Sep - 16 Oct	Delta
22 Sep - 06 Oct	Air France
22 Sep - 15 Oct	Air France
23 Sep - 28 Sep	Delta
24 Sep - 28 Sep	Delta
22 Sep - 16 Oct	Air France
22 Sep - 14 Oct	Air France
16 Sep - 30 Sep	Corendon Dutch Airlines
16 Sep - 27 Sep	Corendon Dutch Airlines
19 Sep - 26 Sep	Delta
23 Sep - 30 Sep	Corendon Dutch Airlines
22 Sep - 28 Sep	TUI.nl

Also check the deals for one-way flights from Amsterdam to Santiago in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Amsterdam to Santiago in September from 759€

Return flights