AirHint found the following cheapest return flights from Amsterdam (AMS) to Santiago (SCL) in December 2025 (see full year).

Return flights

01 Dec - 08 Dec	Delta
02 Dec - 13 Jan	Delta
30 Dec - 14 Jan	Delta
07 Dec - 14 Jan	Delta
31 Dec - 27 Jan	Iberia
31 Dec - 24 Jan	Delta
05 Dec - 09 Dec	Delta
05 Dec - 29 Dec	Iberia
04 Dec - 14 Dec	Iberia
28 Dec - 20 Jan	Delta
28 Dec - 18 Jan	Delta
07 Dec - 21 Dec	Iberia
24 Dec - 20 Jan	Iberia
24 Dec - 22 Jan	Iberia
26 Dec - 23 Jan	Iberia
09 Dec - 21 Dec	Iberia
10 Dec - 12 Dec	Vueling Airlines
10 Dec - 21 Dec	Delta
01 Dec - 31 Dec	Ryanair
12 Dec - 29 Dec	Iberia

Also check the deals for one-way flights from Amsterdam to Santiago in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Amsterdam to Santiago in December from 759€

Return flights