AirHint found the following cheapest return flights from Amsterdam (AMS) to Santiago (SCL) in December 2025 (see full year).

Return flights

02 Dec - 09 Dec	Air Canada
09 Dec - 13 Jan	Delta
09 Dec - 14 Jan	Delta
10 Dec - 13 Jan	Delta
01 Dec - 08 Dec	Air Canada
08 Dec - 16 Jan	Delta
09 Dec - 15 Jan	Delta
24 Dec - 18 Jan	Delta
24 Dec - 17 Jan	Delta
29 Dec - 14 Jan	Delta
29 Dec - 18 Jan	Delta
29 Dec - 19 Jan	Delta
05 Dec - 27 Dec	Delta
01 Dec - 14 Dec	Ryanair
01 Dec - 15 Dec	Ryanair
03 Dec - 14 Dec	Ryanair
03 Dec - 10 Dec	Delta
01 Dec - 19 Dec	Ryanair
04 Dec - 14 Dec	transavia
04 Dec - 15 Dec	transavia

Also check the deals for one-way flights from Amsterdam to Santiago in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Amsterdam to Santiago in December from 744€

Return flights