AirHint found the following cheapest return flights from Amsterdam (AMS) to Panama City (PTY) in September 2025 (see full year).

Return flights

20 Sep - 13 Oct	Iberia
20 Sep - 06 Oct	Iberia
29 Sep - 16 Oct	Air France
20 Sep - 13 Oct	KLM	direct
20 Sep - 06 Oct	KLM	direct
20 Sep - 28 Sep	Air France
17 Sep - 25 Sep	KLM	direct
20 Sep - 28 Sep	KLM	direct
28 Sep - 05 Oct	Air France
19 Sep - 26 Sep	Turkish Airlines
26 Sep - 18 Oct	KLM
20 Sep - 27 Sep	Air France
25 Sep - 28 Sep	Turkish Airlines
20 Sep - 27 Sep	KLM	direct
26 Sep - 18 Oct	KLM	direct
30 Sep - 04 Oct	Ryanair
28 Sep - 05 Oct	KLM	direct
25 Sep - 28 Sep	KLM	direct

Also check the deals for one-way flights from Amsterdam to Panama City in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Amsterdam to Panama City in September from 577€

Return flights