AirHint found the following cheapest one-way flights from Valencia (VLC) to Prague (PRG) in September 2025 (see full year).

One-Way flights

25 Sep	Smart Wings	direct
21 Sep	Smart Wings	direct
27 Sep	Eurowings	direct
23 Sep	Wizz Air Malta
22 Sep	Vueling Airlines
26 Sep	Smart Wings	direct
24 Sep	Ryanair
28 Sep	Ryanair
22 Sep	Smart Wings	direct

Also check the deals for return flights from Valencia to Prague in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest one-way flights from Valencia to Prague in September from 78€

One-Way flights