AirHint found the following cheapest one-way flights from San Jose (SJC) to Santiago (SCL) in December 2025 (see full year).

One-Way flights

08 Dec	Alaska Airlines
25 Dec	Alaska Airlines
06 Dec	Alaska Airlines
15 Dec	Alaska Airlines
12 Dec	Alaska Airlines
23 Dec	Alaska Airlines
13 Dec	Alaska Airlines
18 Dec	Alaska Airlines
21 Dec	Alaska Airlines
20 Dec	Alaska Airlines

Also check the deals for return flights from San Jose to Santiago in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Santiago

Cheap car rent in Santiago

Cheapest one-way flights from San Jose to Santiago in December from 492€

One-Way flights