Cheapest one-way flights from Santiago to Prague in December from 72€

AirHint found the following cheapest one-way flights from Santiago (SCQ) to Prague (PRG) in December 2025 (see full year).

One-Way flights

08 Dec Ryanair
04 Dec Vueling Airlines
07 Dec Vueling Airlines
12 Dec Vueling Airlines
13 Dec Vueling Airlines
11 Dec Vueling Airlines
14 Dec Vueling Airlines
20 Dec Vueling Airlines
05 Dec Vueling Airlines

Also check the deals for return flights from Santiago to Prague in December.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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