Cheapest one-way flights from Santiago to Madrid in May from 447€

AirHint found the following cheapest one-way flights from Santiago (SCL) to Madrid (MAD) in May 2026 (see full year).

One-Way flights

11 May LATAM Airlines Group
25 May LATAM Airlines Group
21 May LATAM Airlines Group
27 May LATAM Airlines Group
26 May LATAM Airlines Group
23 May LATAM Airlines Group
22 May LATAM Airlines Group
28 May Avianca
02 May Avianca
10 May Avianca

Also check the deals for return flights from Santiago to Madrid in May.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Madrid

Cheap car rent in Madrid

Feel free to contact us with any feedback or request another flight research.