Cheapest one-way flights from Santiago to Madrid in April from 462€

AirHint found the following cheapest one-way flights from Santiago (SCL) to Madrid (MAD) in April 2026 (see full year).

One-Way flights

04 Apr Sky Airline
08 Apr LATAM Airlines Group
03 Apr Sky Airline
14 Apr LATAM Airlines Group
06 Apr Aerolíneas Argentinas
18 Apr Sky Airline
01 Apr Avianca
02 Apr Avianca
20 Apr LATAM Airlines Group
16 Apr Avianca

Also check the deals for return flights from Santiago to Madrid in April.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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