Cheapest one-way flights from Santiago to Madrid in April from 461€

AirHint found the following cheapest one-way flights from Santiago (SCL) to Madrid (MAD) in April 2026 (see full year).

One-Way flights

25 Apr LATAM Airlines Group
27 Apr JetSmart
17 Apr Sky Airline
19 Apr LATAM Airlines Group
14 Apr Sky Airline
07 Apr Sky Airline
16 Apr Sky Airline
11 Apr Sky Airline
12 Apr Sky Airline
20 Apr LATAM Airlines Group

Also check the deals for return flights from Santiago to Madrid in April.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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