Cheapest one-way flights from Santiago to Madrid in April from 446€

AirHint found the following cheapest one-way flights from Santiago (SCL) to Madrid (MAD) in April 2026 (see full year).

One-Way flights

12 Apr LATAM Airlines Group
14 Apr LATAM Airlines Group
13 Apr LATAM Airlines Group
20 Apr LATAM Airlines Group
16 Apr LATAM Airlines Group
27 Apr LATAM Airlines Group
09 Apr LATAM Airlines Group
08 Apr LATAM Airlines Group
15 Apr LATAM Airlines Group
10 Apr LATAM Airlines Group

Also check the deals for return flights from Santiago to Madrid in April.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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