Cheapest one-way flights from Santiago to Madrid in December from 402€

AirHint found the following cheapest one-way flights from Santiago (SCL) to Madrid (MAD) in December 2025 (see full year).

One-Way flights

10 Dec Iberia direct
06 Dec Iberia direct
09 Dec Iberia direct
08 Dec Iberia direct
04 Dec Iberia direct
07 Dec Iberia direct
12 Dec Sky Airline
13 Dec Avianca
15 Dec Sky Airline
12 Dec Iberia direct

Also check the deals for return flights from Santiago to Madrid in December.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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