Cheapest one-way flights from Santiago to La Serena in September from 21€

AirHint found the following cheapest one-way flights from Santiago (SCL) to La Serena (LSC) in September 2025 (see full year).

One-Way flights

28 Sep LATAM Airlines Group direct
24 Sep LATAM Airlines Group direct
23 Sep LATAM Airlines Group direct
30 Sep LATAM Airlines Group direct
07 Sep LATAM Airlines Group direct
27 Sep Sky Airline direct
21 Sep Sky Airline direct
26 Sep LATAM Airlines Group direct
20 Sep LATAM Airlines Group direct
25 Sep LATAM Airlines Group direct

Also check the deals for return flights from Santiago to La Serena in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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