Cheapest one-way flights from Santiago to La Serena in October from 22€

AirHint found the following cheapest one-way flights from Santiago (SCL) to La Serena (LSC) in October 2025 (see full year).

One-Way flights

11 Oct LATAM Airlines Group direct
22 Oct LATAM Airlines Group direct
04 Oct LATAM Airlines Group direct
07 Oct LATAM Airlines Group direct
01 Oct LATAM Airlines Group direct
23 Oct JetSmart direct
06 Oct Sky Airline direct
10 Oct JetSmart direct
03 Oct Sky Airline direct
21 Oct Sky Airline direct

Also check the deals for return flights from Santiago to La Serena in October.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in La Serena

Cheap car rent in La Serena

Feel free to contact us with any feedback or request another flight research.