Cheapest one-way flights from San Diego to Madrid in December from 273€

AirHint found the following cheapest one-way flights from San Diego (SAN) to Madrid (MAD) in December 2025 (see full year).

One-Way flights

10 Dec Lufthansa
30 Dec Lufthansa
05 Dec Frontier Airlines
01 Dec Frontier Airlines
29 Dec Lufthansa
12 Dec Frontier Airlines
14 Dec jetBlue
17 Dec WestJet
27 Dec Hawaiian Airlines
18 Dec Frontier Airlines

Also check the deals for return flights from San Diego to Madrid in December.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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