AirHint found the following cheapest one-way flights from Rome (ROM) to Istanbul (SAW) in October 2025 (see full year).

One-Way flights

21 Oct	Wizz Air Malta
14 Oct	Wizz Air Malta
29 Oct	Wizz Air Malta
30 Oct	Wizz Air Malta
27 Oct	Pegasus Airlines	direct
02 Oct	Wizz Air Malta
15 Oct	Wizz Air Malta
21 Oct	Pegasus Airlines	direct
16 Oct	easyJet
17 Oct	easyJet

Also check the deals for return flights from Rome to Istanbul in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest one-way flights from Rome to Istanbul in October from 60€

One-Way flights