AirHint found the following cheapest one-way flights from Portland (PWM) to Charleston (CHS) in December 2025 (see full year).
One-Way flights
| 12 Dec | Breeze Airways | direct | |
| 15 Dec | Breeze Airways | direct | |
| 13 Dec | American Airlines | ||
| 16 Dec | American Airlines | ||
| 17 Dec | American Airlines | ||
| 11 Dec | American Airlines | ||
| 14 Dec | Delta |
Also check the deals for return flights from Portland to Charleston in December.
The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.
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