Cheapest one-way flights from Panama City to Santa Cruz in September from 247€

AirHint found the following cheapest one-way flights from Panama City (PTY) to Santa Cruz (VVI) in September 2025 (see full year).

One-Way flights

25 Sep Avianca
26 Sep Avianca
24 Sep Avianca
24 Sep Copa direct
25 Sep Copa direct
26 Sep Copa direct

Also check the deals for return flights from Panama City to Santa Cruz in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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