Cheapest one-way flights from Prague to Madrid in September from 50€
AirHint found the following cheapest one-way flights from Prague (PRG) to Madrid (MAD) in September 2025 (see full year).
One-Way flights
| 25 Sep | Ryanair | direct | |
| 23 Sep | easyJet | ||
| 16 Sep | Ryanair | direct | |
| 10 Sep | Ryanair | direct | |
| 01 Sep | easyJet | ||
| 17 Sep | easyJet | ||
| 23 Sep | Ryanair | direct | |
| 18 Sep | easyJet | ||
| 09 Sep | easyJet | ||
| 08 Sep | Air Serbia |
Also check the deals for return flights from Prague to Madrid in September.
The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.
